The Blues dropped down to fourth in the Premier League after suffering their second loss in three games, with the Spanish international taking the blame.
Ruben Loftus-Cheek fired the West London side into the lead at Molineux, before Nuno Espirito Santo's men turned the game on its head in the second half.
Raul Jimenez and Diogo Jota netted for Wolves in the space of four minutes to leave Chelsea ten points behind leaders Manchester City.
And fans have been left raging with Alonso's performance, with the ex-Bolton man caught out of position for both goals.
Many supporters are urging Maurizio Sarri to drop the 27-year-old in favour of former Roma star Emerson Palmieri.
One fan tweeted: "I have no words for Marcos Alonso!! Man has dropped a -10/10 performance. What a liability."
While another commented: "Alonso with a another shocker today, start Emerson."
Antother supported said: "Marcos Alonso is disappointing on so many levels. His positioning, crossing all need to improve. Gone back to being his old inconsistent self."
With one simply stating: "Honestly Marcos Alonso is the worst defender in the Prem."
Alonso only recently signed a new five-year deal at Stamford Bridge to keep him at the club until 2023.
A regular in the side since joining from Fiorentina in 2016, he has featured in 17 games in all competitions this season, netting once and providing five assists.
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